A combinatorial library of lipid-like materials for delivery of RNAi therapeutics
A combinatorial library of lipid-like materials for delivery of RNAi therapeutics
About this item
Full title
Author / Creator
Akinc, Akin , Zumbuehl, Andreas , Goldberg, Michael , Leshchiner, Elizaveta S , Busini, Valentina , Hossain, Naushad , Bacallado, Sergio A , Nguyen, David N , Fuller, Jason , Alvarez, Rene , Borodovsky, Anna , Borland, Todd , Constien, Rainer , de Fougerolles, Antonin , Dorkin, J Robert , Narayanannair Jayaprakash, K , Jayaraman, Muthusamy , John, Matthias , Koteliansky, Victor , Manoharan, Muthiah , Nechev, Lubomir , Qin, June , Racie, Timothy , Raitcheva, Denitza , Rajeev, Kallanthottathil G , Sah, Dinah W Y , Soutschek, Jürgen , Toudjarska, Ivanka , Vornlocher, Hans-Peter , Zimmermann, Tracy S , Langer, Robert and Anderson, Daniel G
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
The safe and effective delivery of RNA interference (RNAi) therapeutics remains an important challenge for clinical development. The diversity of current delivery materials remains limited, in part because of their slow, multi-step syntheses. Here we describe a new class of lipid-like delivery molecules, termed lipidoids, as delivery agents for RNA...
Alternative Titles
Full title
A combinatorial library of lipid-like materials for delivery of RNAi therapeutics
Authors, Artists and Contributors
Author / Creator
Zumbuehl, Andreas
Goldberg, Michael
Leshchiner, Elizaveta S
Busini, Valentina
Hossain, Naushad
Bacallado, Sergio A
Nguyen, David N
Fuller, Jason
Alvarez, Rene
Borodovsky, Anna
Borland, Todd
Constien, Rainer
de Fougerolles, Antonin
Dorkin, J Robert
Narayanannair Jayaprakash, K
Jayaraman, Muthusamy
John, Matthias
Koteliansky, Victor
Manoharan, Muthiah
Nechev, Lubomir
Qin, June
Racie, Timothy
Raitcheva, Denitza
Rajeev, Kallanthottathil G
Sah, Dinah W Y
Soutschek, Jürgen
Toudjarska, Ivanka
Vornlocher, Hans-Peter
Zimmermann, Tracy S
Langer, Robert
Anderson, Daniel G
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3014085
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3014085
Other Identifiers
ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/nbt1402
