Log in to save to my catalogue

Tuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sites

Tuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sites

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3021048

Tuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sites

About this item

Full title

Tuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sites

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2011-01, Vol.108 (2), p.598-602

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Selective ion conduction across ion channel pores is central to cellular physiology. To understand the underlying principles of ion selectivity in tetrameric cation channels, we engineered a set of cation channel pores based on the nonselective NaK channel and determined their structures to high resolution. These structures showcase an ensemble of...

Alternative Titles

Full title

Tuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sites

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3021048

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3021048

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1013636108

How to access this item