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NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis

NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3026862

NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis

About this item

Full title

NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis

Publisher

Oxford, UK: Oxford University Press

Journal title

Inflammatory bowel diseases, 2011-06, Vol.17 (6), p.1359-1372

Language

English

Formats

Publication information

Publisher

Oxford, UK: Oxford University Press

More information

Scope and Contents

Contents

Attenuated innate immune responses to the intestinal microbiota have been linked to the pathogenesis of Crohn's disease (CD). Recent genetic studies have revealed that hypofunctional mutations of NLRP3, a member of the NOD-like receptor (NLR) superfamily, are associated with an increased risk of developing CD. NLRP3 is a key component of the inflam...

Alternative Titles

Full title

NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3026862

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3026862

Other Identifiers

ISSN

1078-0998,1536-4844

E-ISSN

1536-4844

DOI

10.1002/ibd.21478

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