Kinetic Scaffolding Mediated by a Phospholipase C-β and Gq Signaling Complex
Kinetic Scaffolding Mediated by a Phospholipase C-β and Gq Signaling Complex
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Publisher
Washington, DC: American Association for the Advancement of Science
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Language
English
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Washington, DC: American Association for the Advancement of Science
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Contents
Transmembrane signals initiated by a broad range of extracellular stimuli converge on nodes that regulate phospholipase C (PLC)-dependent inositol lipid hydrolysis for signal propagation. We describe how heterotrimeric guanine nucleotide-binding proteins (G proteins) activate PLC-βs and in turn are deactivated by these downstream effectors. The 2.7...
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Full title
Kinetic Scaffolding Mediated by a Phospholipase C-β and Gq Signaling Complex
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3046049
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3046049
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ISSN
0036-8075,1095-9203
E-ISSN
1095-9203
DOI
10.1126/science.1193438
