Intrinsic antibody-dependent enhancement of microbial infection in macrophages: disease regulation b...
Intrinsic antibody-dependent enhancement of microbial infection in macrophages: disease regulation by immune complexes
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Publisher
London: Elsevier Ltd
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Language
English
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Publisher
London: Elsevier Ltd
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Scope and Contents
Contents
Summary A wide range of microorganisms can replicate in macrophages, and cell entry of these pathogens via non-neutralising IgG antibody complexes can result in increased intracellular infection through idiosyncratic Fcγ-receptor signalling. The activation of Fcγ receptors usually leads to phagocytosis. Paradoxically, the ligation of monocyte or ma...
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Full title
Intrinsic antibody-dependent enhancement of microbial infection in macrophages: disease regulation by immune complexes
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3057165
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3057165
Other Identifiers
ISSN
1473-3099
E-ISSN
1474-4457
DOI
10.1016/S1473-3099(10)70166-3
