Determinism and stochasticity during maturation of the zebrafish antibody repertoire
Determinism and stochasticity during maturation of the zebrafish antibody repertoire
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
It is thought that the adaptive immune system of immature organisms follows a more deterministic program of antibody creation than is found in adults. We used high-throughput sequencing to characterize the diversifying antibody repertoire in zebrafish over five developmental time points. We found that the immune system begins in a highly stereotype...
Alternative Titles
Full title
Determinism and stochasticity during maturation of the zebrafish antibody repertoire
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3069157
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3069157
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1014277108