Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer
Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Key Points
Epidermal growth factor receptor (
EGFR
)-mutant tumours define a unique subset of non-small-cell lung cancer (NSCLC). These tumours display sensitivity to small-molecule EGFR tyrosine kinase inhibitors (TKIs).
Prospective clinical trials have now validated the correlation between EGFR mutation and TKI sensitivity.
Multipl...
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Full title
Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3072803
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3072803
Other Identifiers
ISSN
1474-175X
E-ISSN
1474-1768
DOI
10.1038/nrc2947