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Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer

Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3072803

Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer

About this item

Full title

Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Cancer, 2010-11, Vol.10 (11), p.760-774

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Key Points
Epidermal growth factor receptor (
EGFR
)-mutant tumours define a unique subset of non-small-cell lung cancer (NSCLC). These tumours display sensitivity to small-molecule EGFR tyrosine kinase inhibitors (TKIs).
Prospective clinical trials have now validated the correlation between EGFR mutation and TKI sensitivity.
Multipl...

Alternative Titles

Full title

Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3072803

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3072803

Other Identifiers

ISSN

1474-175X

E-ISSN

1474-1768

DOI

10.1038/nrc2947

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