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27 results for Chmielecki,+Juliann

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ArticlesPeer ReviewedFull Text
Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer
Author / Creator:Pao, William ; Chmielecki, Juliann
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Cancer, 2010-11, Vol.10 (11), p.760-774
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Anchored multiplex PCR for targeted next-generation sequencing
Author / Creator:Zheng, Zongli ; Liebers, Matthew ; Zhelyazkova, Boryana ; Cao, Yi ; Panditi, Divya ; Lynch, Kerry D ; Chen, Juxiang ; Robinson, Hayley E ; Shim, Hyo Sup ; Chmielecki, Juliann ; Pao, William ; Engelman, Jeffrey A ; Iafrate, A John ; Le, Long Phi
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2014-12, Vol.20 (12), p.1479-1484
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Candidate mechanisms of acquired resistance to first-line osimertinib in EGFR-mutated advanced non-small cell lung cancer
Author / Creator:Chmielecki, Juliann ; Gray, Jhanelle E. ; Cheng, Ying ; Ohe, Yuichiro ; Imamura, Fumio ; Cho, Byoung Chul ; Lin, Meng-Chih ; Majem, Margarita ; Shah, Riyaz ; Rukazenkov, Yuri ; Todd, Alexander ; Markovets, Aleksandra ; Barrett, J. Carl ; Hartmaier, Ryan J. ; Ramalingam, Suresh S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-02, Vol.14 (1), p.1070-1070, Article 1070
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Clinical impact of subclonal EGFR T790M mutations in advanced-stage EGFR-mutant non-small-cell lung cancers
Author / Creator:Vaclova, Tereza ; Grazini, Ursula ; Ward, Lewis ; O’Neill, Daniel ; Markovets, Aleksandra ; Huang, Xiangning ; Chmielecki, Juliann ; Hartmaier, Ryan ; Thress, Kenneth S. ; Smith, Paul D. ; Barrett, J. Carl ; Downward, Julian ; de Bruin, Elza C.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-03, Vol.12 (1), p.1780-1780, Article 1780
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Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden
Author / Creator:Chalmers, Zachary R. ; Connelly, Caitlin F. ; Fabrizio, David ; Gay, Laurie ; Ali, Siraj M. ; Ennis, Riley ; Schrock, Alexa ; Campbell, Brittany ; Shlien, Adam ; Chmielecki, Juliann ; Huang, Franklin ; He, Yuting ; Sun, James ; Tabori, Uri ; Kennedy, Mark ; Lieber, Daniel S. ; Roels, Steven ; White, Jared ; Otto, Geoffrey A. ; Ross, Jeffrey S. ; Garraway, Levi ; Miller, Vincent A. ; Stephens, Phillip J. ; Frampton, Garrett M.
Publisher:England: BioMed Central
Journal title:Genome medicine, 2017-04, Vol.9 (1), p.34-34, Article 34
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Analysis of acquired resistance mechanisms to osimertinib in patients with EGFR-mutated advanced non-small cell lung cancer from the AURA3 trial
Author / Creator:Chmielecki, Juliann ; Mok, Tony ; Wu, Yi-Long ; Han, Ji-Youn ; Ahn, Myung-Ju ; Ramalingam, Suresh S. ; John, Thomas ; Okamoto, Isamu ; Yang, James Chih-Hsin ; Shepherd, Frances A. ; Bulusu, Krishna C. ; Laus, Gianluca ; Collins, Barbara ; Barrett, J. Carl ; Hartmaier, Ryan J. ; Papadimitrakopoulou, Vassiliki
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-02, Vol.14 (1), p.1071-8, Article 1071
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Loss of function JAK1 mutations occur at high frequency in cancers with microsatellite instability and are suggestive of immune evasion
Author / Creator:Albacker, Lee A. ; Wu, Jeremy ; Smith, Peter ; Warmuth, Markus ; Stephens, Philip J. ; Zhu, Ping ; Yu, Lihua ; Chmielecki, Juliann
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-11, Vol.12 (11), p.e0176181-e0176181
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Lung cancers with acquired resistance to EGFR inhibitors occasionally harbor BRAF gene mutations but lack mutations in KRAS, NRAS, or MEK1
Author / Creator:Ohashi, Kadoaki ; Sequist, Lecia V ; Arcila, Maria E ; Moran, Teresa ; Chmielecki, Juliann ; Lin, Ya-Lun ; Pan, Yumei ; Wang, Lu ; de Stanchina, Elisa ; Shien, Kazuhiko ; Aoe, Keisuke ; Toyooka, Shinichi ; Kiura, Katsuyuki ; Fernandez-Cuesta, Lynnette ; Fidias, Panos ; Yang, James Chih-Hsin ; Miller, Vincent A ; Riely, Gregory J ; Kris, Mark G ; Engelman, Jeffrey A ; Vnencak-Jones, Cindy L ; Dias-Santagata, Dora ; Ladanyi, Marc ; Pao, William
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-07, Vol.109 (31), p.E2127-E2133
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Induction of BIM Is Essential for Apoptosis Triggered by EGFR Kinase Inhibitors in Mutant EGFR-Dependent Lung Adenocarcinomas
Author / Creator:Gong, Yixuan ; Somwar, Romel ; Politi, Katerina ; Balak, Marissa ; Chmielecki, Juliann ; Jiang, Xuejun ; Pao, William
Publisher:United States: Public Library of Science
Journal title:PLoS medicine, 2007-10, Vol.4 (10), p.e294-e294
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ArticlesPeer ReviewedFull Text
FGFR1 and NTRK3 actionable alterations in “Wild-Type” gastrointestinal stromal tumors
Author / Creator:Shi, Eileen ; Chmielecki, Juliann ; Tang, Chih-Min ; Wang, Kai ; Heinrich, Michael C. ; Kang, Guhyun ; Corless, Christopher L. ; Hong, David ; Fero, Katherine E. ; Murphy, James D. ; Fanta, Paul T. ; Ali, Siraj M. ; De Siena, Martina ; Burgoyne, Adam M. ; Movva, Sujana ; Madlensky, Lisa ; Heestand, Gregory M. ; Trent, Jonathan C. ; Kurzrock, Razelle ; Morosini, Deborah ; Ross, Jeffrey S. ; Harismendy, Olivier ; Sicklick, Jason K.
Publisher:England: BioMed Central Ltd
Journal title:Journal of translational medicine, 2016-12, Vol.14 (1), p.339-339, Article 339
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ArticlesPeer ReviewedFull Text
A Pan-Cancer Analysis of Transcriptome Changes Associated with Somatic Mutations in U2AF1 Reveals Commonly Altered Splicing Events
Author / Creator:Brooks, Angela N. ; Choi, Peter S. ; de Waal, Luc ; Sharifnia, Tanaz ; Imielinski, Marcin ; Saksena, Gordon ; Pedamallu, Chandra Sekhar ; Sivachenko, Andrey ; Rosenberg, Mara ; Chmielecki, Juliann ; Lawrence, Michael S. ; DeLuca, David S. ; Getz, Gad ; Meyerson, Matthew
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-01, Vol.9 (1), p.e87361-e87361
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ArticlesPeer ReviewedFull Text
Comprehensive genomic profiling of inflammatory breast cancer cases reveals a high frequency of clinically relevant genomic alterations
Author / Creator:Ross, Jeffrey S. ; Ali, Siraj M. ; Wang, Kai ; Khaira, Depinder ; Palma, Norma A. ; Chmielecki, Juliann ; Palmer, Gary A. ; Morosini, Deborah ; Elvin, Julia A. ; Fernandez, Sandra V. ; Miller, Vincent A. ; Stephens, Philip J. ; Cristofanilli, Massimo
Publisher:New York: Springer US
Journal title:Breast cancer research and treatment, 2015-11, Vol.154 (1), p.155-162
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ArticlesPeer ReviewedFull Text
Author Correction: Candidate mechanisms of acquired resistance to first-line osimertinib in EGFR-mutated advanced non-small cell lung cancer
Author / Creator:Chmielecki, Juliann ; Gray, Jhanelle E. ; Cheng, Ying ; Ohe, Yuichiro ; Imamura, Fumio ; Cho, Byoung Chul ; Lin, Meng-Chih ; Majem, Margarita ; Shah, Riyaz ; Rukazenkov, Yuri ; Todd, Alexander ; Markovets, Aleksandra ; Barrett, J. Carl ; Hartmaier, Ryan J. ; Ramalingam, Suresh S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-06, Vol.14 (1), p.3179-3179, Article 3179
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ArticlesPeer ReviewedFull Text
tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancers
Author / Creator:Veeriah, Selvaraju ; Brennan, Cameron ; Meng, Shasha ; Singh, Bhuvanesh ; Fagin, James A ; Solit, David B ; Paty, Philip B ; Rohle, Dan ; Vivanco, Igor ; Chmielecki, Juliann ; Pao, William ; Ladanyi, Marc ; Gerald, William L ; Liau, Linda ; Cloughesy, Timothy C ; Mischel, Paul S ; Sander, Chris ; Taylor, Barry ; Schultz, Nikolaus ; Major, John ; Heguy, Adriana ; Fang, Fang ; Mellinghoff, Ingo K ; Chan, Timothy A
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2009-06, Vol.106 (23), p.9435-9440
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ArticlesPeer ReviewedFull Text
Anchored multiplex FOR for targeted next-generation sequencing
Author / Creator:Zheng, Z ; Liebers, M ; Zhelyazkova, B ; Cao, Y ; Panditi, D ; Lynch, KD ; Chen, J ; Robinson, HE ; Shim, HS ; Chmielecki, J
Journal title:Nature medicine, 2014-12, Vol.20 (12), p.1479
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ArticlesPeer ReviewedFull Text
Whole-exome sequencing identifies a recurrent NAB2-STAT6 fusion in solitary fibrous tumors
Author / Creator:Chmielecki, Juliann ; Crago, Aimee M ; Rosenberg, Mara ; O'Connor, Rachael ; Walker, Sarah R ; Ambrogio, Lauren ; Auclair, Daniel ; McKenna, Aaron ; Heinrich, Michael C ; Frank, David A ; Meyerson, Matthew
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2013-02, Vol.45 (2), p.131-132
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A phase Ib study of adavosertib, a selective Wee1 inhibitor, in patients with locally advanced or metastatic solid tumors
Author / Creator:Falchook, Gerald S ; Sachdev, Jasgit ; Imedio, Esteban Rodrigo ; Kumar, Sanjeev ; Mugundu, Ganesh M ; Jenkins, Suzanne ; Chmielecki, Juliann ; Jones, Suzanne ; Spigel, David R ; Johnson, Melissa
Publisher:New York: Springer US
Journal title:Investigational new drugs, 2023-06, Vol.41 (3), p.493-502
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An ErbB2 splice variant lacking exon 16 drives lung carcinoma
Author / Creator:Smith, Harvey W. ; Yang, Lei ; Ling, Chen ; Walsh, Arlan ; Martinez, Victor D. ; Boucher, Jonathan ; Zuo, Dongmei ; Sokol, Ethan S. ; Pavlick, Dean C. ; Frampton, Garrett M. ; Chmielecki, Juliann ; Jones, Laura M. ; Roux, Philippe P. ; Lockwood, William W. ; Muller, William J.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-08, Vol.117 (33), p.20139-20148
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A Phase Ib Study Assessing the Safety, Tolerability, and Efficacy of the First-in-Class Wee1 Inhibitor Adavosertib (AZD1775) as Monotherapy in Patients with Advanced Solid Tumors
Author / Creator:Bauer, Todd M. ; Moore, Kathleen N. ; Rader, Janet S. ; Simpkins, Fiona ; Mita, Alain C. ; Beck, J. Thaddeus ; Hart, Lowell ; Chu, Quincy ; Oza, Amit ; Tinker, Anna V. ; Imedio, Esteban Rodrigo ; Kumar, Sanjeev ; Mugundu, Ganesh ; Jenkins, Suzanne ; Chmielecki, Juliann ; Jones, Suzanne ; Spigel, David ; Fu, Siqing
Publisher:Cham: Springer International Publishing
Journal title:Targeted oncology, 2023-07, Vol.18 (4), p.517-530
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Genomic analysis of 63,220 tumors reveals insights into tumor uniqueness and targeted cancer immunotherapy strategies
Author / Creator:Hartmaier, Ryan J. ; Charo, Jehad ; Fabrizio, David ; Goldberg, Michael E. ; Albacker, Lee A. ; Pao, William ; Chmielecki, Juliann
Publisher:England: BioMed Central Ltd
Journal title:Genome medicine, 2017-02, Vol.9 (1), p.16-16, Article 16
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Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer

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Anchored multiplex PCR for targeted next-generation sequencing

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Candidate mechanisms of acquired resistance to first-line osimertinib in EGFR-mutated advanced non-small cell lung cancer

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Clinical impact of subclonal EGFR T790M mutations in advanced-stage EGFR-mutant non-small-cell lung cancers

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Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden

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Analysis of acquired resistance mechanisms to osimertinib in patients with EGFR-mutated advanced non-small cell lung cancer from the AURA3 trial

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Loss of function JAK1 mutations occur at high frequency in cancers with microsatellite instability and are suggestive of immune evasion

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Lung cancers with acquired resistance to EGFR inhibitors occasionally harbor BRAF gene mutations but lack mutations in KRAS, NRAS, or MEK1

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Induction of BIM Is Essential for Apoptosis Triggered by EGFR Kinase Inhibitors in Mutant EGFR-Dependent Lung Adenocarcinomas

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FGFR1 and NTRK3 actionable alterations in “Wild-Type” gastrointestinal stromal tumors

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A Pan-Cancer Analysis of Transcriptome Changes Associated with Somatic Mutations in U2AF1 Reveals Commonly Altered Splicing Events

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Comprehensive genomic profiling of inflammatory breast cancer cases reveals a high frequency of clinically relevant genomic alterations

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Author Correction: Candidate mechanisms of acquired resistance to first-line osimertinib in EGFR-mutated advanced non-small cell lung cancer

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tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancers

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Anchored multiplex FOR for targeted next-generation sequencing

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Whole-exome sequencing identifies a recurrent NAB2-STAT6 fusion in solitary fibrous tumors

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A phase Ib study of adavosertib, a selective Wee1 inhibitor, in patients with locally advanced or metastatic solid tumors

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An ErbB2 splice variant lacking exon 16 drives lung carcinoma

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A Phase Ib Study Assessing the Safety, Tolerability, and Efficacy of the First-in-Class Wee1 Inhibitor Adavosertib (AZD1775) as Monotherapy in Patients with Advanced Solid Tumors

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Genomic analysis of 63,220 tumors reveals insights into tumor uniqueness and targeted cancer immunotherapy strategies

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