A transgenic mouse for in vivo detection of endogenous labeled mRNA
A transgenic mouse for in vivo detection of endogenous labeled mRNA
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Tagging the endogenous beta-actin locus with an MS2-binding cassette allows live-cell imaging of mRNA in real time.
Live-cell single mRNA imaging is a powerful tool but has been restricted in higher eukaryotes to artificial cell lines and reporter genes. We describe an approach that enables live-cell imaging of single endogenous labeled mRNA mol...
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A transgenic mouse for in vivo detection of endogenous labeled mRNA
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3076588
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3076588
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ISSN
1548-7091
E-ISSN
1548-7105
DOI
10.1038/nmeth.1551
