Deletion of the Slo3 gene abolishes alkalization-activated K⁺ current in mouse spermatozoa
Deletion of the Slo3 gene abolishes alkalization-activated K⁺ current in mouse spermatozoa
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Mouse spermatozoa express a pH-dependent K⁺ current (KSper) thought to be composed of subunits encoded by the Slo3 gene. However, the equivalence of KSper and S/o3-dependent current remains uncertain, because heterologous expression of S/o3 results in currents that are less effectively activated by alkalization than are native KSper currents. Here,...
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Full title
Deletion of the Slo3 gene abolishes alkalization-activated K⁺ current in mouse spermatozoa
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3078394
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3078394
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1100240108
