TRIM5 is an innate immune sensor for the retrovirus capsid lattice
TRIM5 is an innate immune sensor for the retrovirus capsid lattice
About this item
Full title
Author / Creator
Pertel, Thomas , Hausmann, Stéphane , Morger, Damien , Züger, Sara , Guerra, Jessica , Lascano, Josefina , Reinhard, Christian , Santoni, Federico A. , Uchil, Pradeep D. , Chatel, Laurence , Bisiaux, Aurélie , Albert, Matthew L. , Strambio-De-Castillia, Caterina , Mothes, Walther , Pizzato, Massimo , Grütter, Markus G. and Luban, Jeremy
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Multi-layered antiviral activity of TRIM5
TRIM5 is an E3 ubiquitin ligase with known antiretroviral restriction factor activity, although the mechanisms involved are poorly understood. Luban and colleagues now demonstrate that TRIM5 activates innate immune signalling pathways and acts as a pattern recognition receptor specific for the retrovirus...
Alternative Titles
Full title
TRIM5 is an innate immune sensor for the retrovirus capsid lattice
Authors, Artists and Contributors
Author / Creator
Hausmann, Stéphane
Morger, Damien
Züger, Sara
Guerra, Jessica
Lascano, Josefina
Reinhard, Christian
Santoni, Federico A.
Uchil, Pradeep D.
Chatel, Laurence
Bisiaux, Aurélie
Albert, Matthew L.
Strambio-De-Castillia, Caterina
Mothes, Walther
Pizzato, Massimo
Grütter, Markus G.
Luban, Jeremy
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3081621
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3081621
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature09976
