Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in mice
Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in mice
About this item
Full title
Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
George Vassiliou, Allan Bradley and colleagues perform a Sleeping Beauty transposon mutagenesis screen to identify insertions that cooperate with mutant
Npm1
to produce acute myeloid leukemia (AML) in mice. They observed mutually exclusive integrations in
Csf2
,
Flt3
or
Rasgrp1
in a high percentage of cases, providing insigh...
Alternative Titles
Full title
Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in mice
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3084174
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3084174
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.796
