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The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis

The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3094110

The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis

About this item

Full title

The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis

Publisher

Chichester, UK: John Wiley & Sons, Ltd

Journal title

The EMBO journal, 2011-04, Vol.30 (7), p.1357-1375

Language

English

Formats

Publication information

Publisher

Chichester, UK: John Wiley & Sons, Ltd

More information

Scope and Contents

Contents

The endoplasmic reticulum (ER) is the cellular organelle responsible for protein folding and assembly, lipid and sterol biosynthesis, and calcium storage. The unfolded protein response (UPR) is an adaptive intracellular stress response to accumulation of unfolded or misfolded proteins in the ER. In this study, we show that the most conserved UPR se...

Alternative Titles

Full title

The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3094110

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3094110

Other Identifiers

ISSN

0261-4189

E-ISSN

1460-2075

DOI

10.1038/emboj.2011.52

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