Multiple Genetic Backgrounds of the Amplified Plasmodium falciparum Multidrug Resistance (pfmdr1) Ge...
Multiple Genetic Backgrounds of the Amplified Plasmodium falciparum Multidrug Resistance (pfmdr1) Gene and Selective Sweep of 184F Mutation in Cambodia
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Author / Creator
Vinayak, Sumiti , Alam, Md Tauqeer , Sem, Rithy , Shah, Naman K. , Susanti, Augustina I. , Lim, Pharath , Muth, Sinuon , Maguire, Jason D. , Rogers, William O. , Fandeur, Thierry , Barnwell, John W. , Escalante, Ananias A. , Wongsrichanalai, Chansuda , Ariey, Frederick , Meshnick, Steven R. and Udhayakumar, Venkatachalam
Publisher
Oxford: The University of Chicago Press
Journal title
Language
English
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Publisher
Oxford: The University of Chicago Press
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Contents
Background. The emergence of artesunate-mefloquine (AS+MQ)-resistant Plasmodium falciparum in the Thailand- Cambodia region is a major concern for malaria control. Studies indicate that copy number increase and key alleles in the pfmdr1 gene are associated with AS+MQ resistance. In the present study, we investigated evidence for a selective sweep a...
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Full title
Multiple Genetic Backgrounds of the Amplified Plasmodium falciparum Multidrug Resistance (pfmdr1) Gene and Selective Sweep of 184F Mutation in Cambodia
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3096139
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3096139
Other Identifiers
ISSN
0022-1899
E-ISSN
1537-6613
DOI
10.1086/651949
