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LMP1 association with CD63 in endosomes and secretion via exosomes limits constitutive NF-κB activat...

LMP1 association with CD63 in endosomes and secretion via exosomes limits constitutive NF-κB activat...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3117644

LMP1 association with CD63 in endosomes and secretion via exosomes limits constitutive NF-κB activation

About this item

Full title

LMP1 association with CD63 in endosomes and secretion via exosomes limits constitutive NF-κB activation

Publisher

Chichester, UK: John Wiley & Sons, Ltd

Journal title

The EMBO journal, 2011-06, Vol.30 (11), p.2115-2129

Language

English

Formats

Publication information

Publisher

Chichester, UK: John Wiley & Sons, Ltd

More information

Scope and Contents

Contents

The ubiquitous Epstein Barr virus (EBV) exploits human B‐cell development to establish a persistent infection in ∼90% of the world population. Constitutive activation of NF‐κB by the viral oncogene latent membrane protein 1 (LMP1) has an important role in persistence, but is a risk factor for EBV‐associated lymphomas. Here, we demonstrate that endo...

Alternative Titles

Full title

LMP1 association with CD63 in endosomes and secretion via exosomes limits constitutive NF-κB activation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3117644

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3117644

Other Identifiers

ISSN

0261-4189

E-ISSN

1460-2075

DOI

10.1038/emboj.2011.123

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