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Defining the geometry of the two-component proteasome degron

Defining the geometry of the two-component proteasome degron

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3129032

Defining the geometry of the two-component proteasome degron

About this item

Full title

Defining the geometry of the two-component proteasome degron

Publisher

New York: Nature Publishing Group US

Journal title

Nature chemical biology, 2011-03, Vol.7 (3), p.161-167

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The geometric relationship between the two protein degradation signals of proteasome substrates, the polyubiquitin chain and the unfolded region, is dictated by the locations of their recognition sites on the proteasome.
The eukaryotic 26S proteasome controls cellular processes by degrading specific regulatory proteins. Most proteins are targete...

Alternative Titles

Full title

Defining the geometry of the two-component proteasome degron

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3129032

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3129032

Other Identifiers

ISSN

1552-4450

E-ISSN

1552-4469

DOI

10.1038/nchembio.521

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