Protein targeting and degradation are coupled for elimination of mislocalized proteins
Protein targeting and degradation are coupled for elimination of mislocalized proteins
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Removal of 'spare' proteins
Membrane proteins that fail to be delivered to the endoplasmic reticulum must be rapidly degraded to avoid inappropriate aggregation and disruption of protein homeostasis. The mechanism of this process of mislocalized protein (MLP) degradation is unknown. Here Bag6, a chaperone complex involved in protein targeting, i...
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Full title
Protein targeting and degradation are coupled for elimination of mislocalized proteins
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3150218
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3150218
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature10181
