Regulation of angiogenesis by a non-canonical Wnt–Flt1 pathway in myeloid cells
Regulation of angiogenesis by a non-canonical Wnt–Flt1 pathway in myeloid cells
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Author / Creator
Stefater III, James A. , Lewkowich, Ian , Rao, Sujata , Mariggi, Giovanni , Carpenter, April C. , Burr, Adam R. , Fan, Jieqing , Ajima, Rieko , Molkentin, Jeffery D. , Williams, Bart O. , Wills-Karp, Marsha , Pollard, Jeffrey W. , Yamaguchi, Terry , Ferrara, Napoleone , Gerhardt, Holger and Lang, Richard A.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Angiogenesis regulation in the retina
Richard Lang and colleagues identify a mechanism by which myeloid cells regulate the pattern of blood-vessel branching in the post-natal retina. They show that macrophages inhibit branching by secreting Wnt ligands that use a non-canonical pathway to induce secretion of the VEGF inhibitory receptor Flt1.
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Alternative Titles
Full title
Regulation of angiogenesis by a non-canonical Wnt–Flt1 pathway in myeloid cells
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3214992
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3214992
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature10085
