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Epidermal growth factor receptor mutation in combination with expression of MIG6 alters gefitinib se...

Epidermal growth factor receptor mutation in combination with expression of MIG6 alters gefitinib se...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3224393

Epidermal growth factor receptor mutation in combination with expression of MIG6 alters gefitinib sensitivity

About this item

Full title

Epidermal growth factor receptor mutation in combination with expression of MIG6 alters gefitinib sensitivity

Publisher

England: BioMed Central Ltd

Journal title

BMC systems biology, 2011-02, Vol.5 (1), p.29-29, Article 29

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Epidermal growth factor receptor (EGFR) signaling plays an important role in the regulation of cell proliferation, survival, metastasis, and invasion in various tumors. Earlier studies showed that the EGFR is frequently overexpressed in non-small-cell lung cancer (NSCLC) and EGFR mutations at specific amino acid residues in the kinase domain induce...

Alternative Titles

Full title

Epidermal growth factor receptor mutation in combination with expression of MIG6 alters gefitinib sensitivity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3224393

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3224393

Other Identifiers

ISSN

1752-0509

E-ISSN

1752-0509

DOI

10.1186/1752-0509-5-29

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