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Peripherally Applied Aβ-Containing Inoculates Induce Cerebral β-Amyloidosis

Peripherally Applied Aβ-Containing Inoculates Induce Cerebral β-Amyloidosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3233904

Peripherally Applied Aβ-Containing Inoculates Induce Cerebral β-Amyloidosis

About this item

Full title

Peripherally Applied Aβ-Containing Inoculates Induce Cerebral β-Amyloidosis

Publisher

Washington, DC: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2010-11, Vol.330 (6006), p.980-982

Language

English

Formats

Publication information

Publisher

Washington, DC: American Association for the Advancement of Science

More information

Scope and Contents

Contents

The intracerebral injection of β-amyloid-containing brain extracts can induce cerebral β-amyloidosis and associated pathologies in susceptible hosts. We found that intraperitoneal inoculation with β-amyloid-rich extracts induced β-amyloidosis in the brains of β-amyloid precursor protein transgenic mice after prolonged incubation times.

Alternative Titles

Full title

Peripherally Applied Aβ-Containing Inoculates Induce Cerebral β-Amyloidosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3233904

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3233904

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1194516

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