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Inflammasome components Asc and caspase-1 mediate biomaterial-induced inflammation and foreign body...

Inflammasome components Asc and caspase-1 mediate biomaterial-induced inflammation and foreign body...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3250158

Inflammasome components Asc and caspase-1 mediate biomaterial-induced inflammation and foreign body response

About this item

Full title

Inflammasome components Asc and caspase-1 mediate biomaterial-induced inflammation and foreign body response

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2011-12, Vol.108 (50), p.20095-20100

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Implantation of biomaterials and devices into soft tissues leads to the development of the foreign body response (FBR), which can interfere with implant function and eventually lead to failure. The FBR consists of overlapping acute and persistent inflammatory phases coupled with collagenous encapsulation and currently there are no therapeutic optio...

Alternative Titles

Full title

Inflammasome components Asc and caspase-1 mediate biomaterial-induced inflammation and foreign body response

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3250158

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3250158

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1105152108

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