Verapamil Results in Increased Blood Levels of Oncolytic Adenovirus in Treatment of Patients With Ad...
Verapamil Results in Increased Blood Levels of Oncolytic Adenovirus in Treatment of Patients With Advanced Cancer
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Publisher
United States: Elsevier Inc
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Language
English
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United States: Elsevier Inc
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Contents
Calcium channel blockers including verapamil have been proposed to enhance release and antitumor efficacy of oncolytic adenoviruses in preclinical studies but this has not been studied in humans before. Here, we studied if verapamil leads to increased replication of oncolytic adenovirus in cancer patients, as measured by release of virions from tum...
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Full title
Verapamil Results in Increased Blood Levels of Oncolytic Adenovirus in Treatment of Patients With Advanced Cancer
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3255582
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3255582
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ISSN
1525-0016
E-ISSN
1525-0024
DOI
10.1038/mt.2011.230
