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Silencing of microRNA‐21 in vivo ameliorates autoimmune splenomegaly in lupus mice

Silencing of microRNA‐21 in vivo ameliorates autoimmune splenomegaly in lupus mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3258486

Silencing of microRNA‐21 in vivo ameliorates autoimmune splenomegaly in lupus mice

About this item

Full title

Silencing of microRNA‐21 in vivo ameliorates autoimmune splenomegaly in lupus mice

Publisher

London: Nature Publishing Group UK

Journal title

EMBO molecular medicine, 2011-10, Vol.3 (10), p.605-615

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

MicroRNAs (miRNAs) have been implicated in B cell lineage commitment, regulation of T cell differentiation, TCR signalling, regulation of IFN signalling, and numerous other immunological processes. However, their function in autoimmunity, and specifically in systemic lupus erythematosus (SLE), remains poorly understood. B6.Sle123 is a spontaneous g...

Alternative Titles

Full title

Silencing of microRNA‐21 in vivo ameliorates autoimmune splenomegaly in lupus mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3258486

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3258486

Other Identifiers

ISSN

1757-4676

E-ISSN

1757-4684

DOI

10.1002/emmm.201100171

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