Structure of a novel phosphotyrosine-binding domain in Hakai that targets E-cadherin
Structure of a novel phosphotyrosine-binding domain in Hakai that targets E-cadherin
About this item
Full title
Author / Creator
BROOKHAVEN NATIONAL LABORATORY (BNL) , Mukherjee, Manjeet , Chow, Soah Yee , Yusoff, Permeen , Seetharaman, J , Ng, Cherlyn , Sinniah, Saravanan , Koh, Xiao Woon , Asgar, Nur Farehan M , Li, Dan , Yim, Daniel , Jackson, Rebecca A , Yew, Jingxi , Qian, Jingru , Iyu, Audrey , Lim, Yoon Pin , Zhou, Xingding , Sze, Siu Kwan , Guy, Graeme R and Sivaraman, J
Publisher
Chichester, UK: John Wiley & Sons, Ltd
Journal title
Language
English
Formats
Publication information
Publisher
Chichester, UK: John Wiley & Sons, Ltd
Subjects
More information
Scope and Contents
Contents
Phosphotyrosine‐binding domains, typified by the SH2 (
S
rc
h
omology 2) and PTB domains, are critical upstream components of signal transduction pathways. The E3 ubiquitin ligase Hakai targets tyrosine‐phosphorylated E‐cadherin via an uncharacterized domain. In this study, the crystal structure of Hakai (amino acids 106–206) revealed t...
Alternative Titles
Full title
Structure of a novel phosphotyrosine-binding domain in Hakai that targets E-cadherin
Authors, Artists and Contributors
Author / Creator
Mukherjee, Manjeet
Chow, Soah Yee
Yusoff, Permeen
Seetharaman, J
Ng, Cherlyn
Sinniah, Saravanan
Koh, Xiao Woon
Asgar, Nur Farehan M
Li, Dan
Yim, Daniel
Jackson, Rebecca A
Yew, Jingxi
Qian, Jingru
Iyu, Audrey
Lim, Yoon Pin
Zhou, Xingding
Sze, Siu Kwan
Guy, Graeme R
Sivaraman, J
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3298002
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3298002
Other Identifiers
ISSN
0261-4189
E-ISSN
1460-2075
DOI
10.1038/emboj.2011.496
