The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte tr...
The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice
About this item
Full title
Author / Creator
Fukuhara, Shigetomo , Simmons, Szandor , Kawamura, Shunsuke , Inoue, Asuka , Orba, Yasuko , Tokudome, Takeshi , Sunden, Yuji , Arai, Yuji , Moriwaki, Kazumasa , Ishida, Junji , Uemura, Akiyoshi , Kiyonari, Hiroshi , Abe, Takaya , Fukamizu, Akiyoshi , Hirashima, Masanori , Sawa, Hirofumi , Aoki, Junken , Ishii, Masaru and Mochizuki, Naoki
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
The bioactive lysophospholipid mediator sphingosine-1-phosphate (S1P) promotes the egress of newly formed T cells from the thymus and the release of immature B cells from the bone marrow. It has remained unclear, however, where and how S1P is released. Here, we show that in mice, the S1P transporter spinster homolog 2 (Spns2) is responsible for the...
Alternative Titles
Full title
The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice
Authors, Artists and Contributors
Author / Creator
Simmons, Szandor
Kawamura, Shunsuke
Inoue, Asuka
Orba, Yasuko
Tokudome, Takeshi
Sunden, Yuji
Arai, Yuji
Moriwaki, Kazumasa
Ishida, Junji
Uemura, Akiyoshi
Kiyonari, Hiroshi
Abe, Takaya
Fukamizu, Akiyoshi
Hirashima, Masanori
Sawa, Hirofumi
Aoki, Junken
Ishii, Masaru
Mochizuki, Naoki
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3314466
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3314466
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI60746
