The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
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Author / Creator
Barretina, Jordi , Caponigro, Giordano , Stransky, Nicolas , Venkatesan, Kavitha , Margolin, Adam A. , Kim, Sungjoon , Wilson, Christopher J. , Lehár, Joseph , Kryukov, Gregory V. , Sonkin, Dmitriy , Reddy, Anupama , Liu, Manway , Murray, Lauren , Berger, Michael F. , Monahan, John E. , Morais, Paula , Meltzer, Jodi , Korejwa, Adam , Jané-Valbuena, Judit , Mapa, Felipa A. , Thibault, Joseph , Bric-Furlong, Eva , Raman, Pichai , Shipway, Aaron , Engels, Ingo H. , Cheng, Jill , Yu, Guoying K. , Yu, Jianjun , Aspesi, Peter , de Silva, Melanie , Jagtap, Kalpana , Jones, Michael D. , Wang, Li , Hatton, Charles , Palescandolo, Emanuele , Gupta, Supriya , Mahan, Scott , Sougnez, Carrie , Onofrio, Robert C. , Liefeld, Ted , MacConaill, Laura , Winckler, Wendy , Reich, Michael , Li, Nanxin , Mesirov, Jill P. , Gabriel, Stacey B. , Getz, Gad , Ardlie, Kristin , Chan, Vivien , Myer, Vic E. , Weber, Barbara L. , Porter, Jeff , Warmuth, Markus , Finan, Peter , Harris, Jennifer L. , Meyerson, Matthew , Golub, Todd R. , Morrissey, Michael P. , Sellers, William R. , Schlegel, Robert and Garraway, Levi A.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The Cancer Cell Line Encyclopedia presents the first results from a large-scale screen of some 947 cancer cell lines with 24 anticancer drugs, with the aim of identifying specific genomic alterations and gene expression profiles associated with selective sensitivity or resistance to potential therapeutic agents.
Large-scale cancer cell line scre...
Alternative Titles
Full title
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
Authors, Artists and Contributors
Author / Creator
Caponigro, Giordano
Stransky, Nicolas
Venkatesan, Kavitha
Margolin, Adam A.
Kim, Sungjoon
Wilson, Christopher J.
Lehár, Joseph
Kryukov, Gregory V.
Sonkin, Dmitriy
Reddy, Anupama
Liu, Manway
Murray, Lauren
Berger, Michael F.
Monahan, John E.
Morais, Paula
Meltzer, Jodi
Korejwa, Adam
Jané-Valbuena, Judit
Mapa, Felipa A.
Thibault, Joseph
Bric-Furlong, Eva
Raman, Pichai
Shipway, Aaron
Engels, Ingo H.
Cheng, Jill
Yu, Guoying K.
Yu, Jianjun
Aspesi, Peter
de Silva, Melanie
Jagtap, Kalpana
Jones, Michael D.
Wang, Li
Hatton, Charles
Palescandolo, Emanuele
Gupta, Supriya
Mahan, Scott
Sougnez, Carrie
Onofrio, Robert C.
Liefeld, Ted
MacConaill, Laura
Winckler, Wendy
Reich, Michael
Li, Nanxin
Mesirov, Jill P.
Gabriel, Stacey B.
Getz, Gad
Ardlie, Kristin
Chan, Vivien
Myer, Vic E.
Weber, Barbara L.
Porter, Jeff
Warmuth, Markus
Finan, Peter
Harris, Jennifer L.
Meyerson, Matthew
Golub, Todd R.
Morrissey, Michael P.
Sellers, William R.
Schlegel, Robert
Garraway, Levi A.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3320027
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3320027
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature11003
