Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
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Author / Creator
Puente, Xose S. , Pinyol, Magda , Quesada, Víctor , Conde, Laura , Ordóñez, Gonzalo R. , Villamor, Neus , Escaramis, Georgia , Jares, Pedro , Beà, Sílvia , González-Díaz, Marcos , Bassaganyas, Laia , Baumann, Tycho , Juan, Manel , López-Guerra, Mónica , Colomer, Dolors , Tubío, José M. C. , López, Cristina , Navarro, Alba , Tornador, Cristian , Aymerich, Marta , Rozman, María , Hernández, Jesús M. , Puente, Diana A. , Freije, José M. P. , Velasco, Gloria , Gutiérrez-Fernández, Ana , Costa, Dolors , Carrió, Anna , Guijarro, Sara , Enjuanes, Anna , Hernández, Lluís , Yagüe, Jordi , Nicolás, Pilar , Romeo-Casabona, Carlos M. , Himmelbauer, Heinz , Castillo, Ester , Dohm, Juliane C. , de Sanjosé, Silvia , Piris, Miguel A. , de Alava, Enrique , Miguel, Jesús San , Royo, Romina , Gelpí, Josep L. , Torrents, David , Orozco, Modesto , Pisano, David G. , Valencia, Alfonso , Guigó, Roderic , Bayés, Mónica , Heath, Simon , Gut, Marta , Klatt, Peter , Marshall, John , Raine, Keiran , Stebbings, Lucy A. , Futreal, P. Andrew , Stratton, Michael R. , Campbell, Peter J. , Gut, Ivo , López-Guillermo, Armando , Estivill, Xavier , Montserrat, Emili , López-Otín, Carlos and Campo, Elías
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Leukaemia-linked gene mutations
Analysis of the genomes of four patients with chronic lymphocytic leukaemia, and validation in more than 300 patients, has identified four genes —
NOTCH1
,
MYD88
,
XPO1
and
KLHL6
— that are recurrently mutated in the condition. Mutations in
NOTCH1
,
MYD88
and
XPO1
are thou...
Alternative Titles
Full title
Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
Authors, Artists and Contributors
Author / Creator
Pinyol, Magda
Quesada, Víctor
Conde, Laura
Ordóñez, Gonzalo R.
Villamor, Neus
Escaramis, Georgia
Jares, Pedro
Beà, Sílvia
González-Díaz, Marcos
Bassaganyas, Laia
Baumann, Tycho
Juan, Manel
López-Guerra, Mónica
Colomer, Dolors
Tubío, José M. C.
López, Cristina
Navarro, Alba
Tornador, Cristian
Aymerich, Marta
Rozman, María
Hernández, Jesús M.
Puente, Diana A.
Freije, José M. P.
Velasco, Gloria
Gutiérrez-Fernández, Ana
Costa, Dolors
Carrió, Anna
Guijarro, Sara
Enjuanes, Anna
Hernández, Lluís
Yagüe, Jordi
Nicolás, Pilar
Romeo-Casabona, Carlos M.
Himmelbauer, Heinz
Castillo, Ester
Dohm, Juliane C.
de Sanjosé, Silvia
Piris, Miguel A.
de Alava, Enrique
Miguel, Jesús San
Royo, Romina
Gelpí, Josep L.
Torrents, David
Orozco, Modesto
Pisano, David G.
Valencia, Alfonso
Guigó, Roderic
Bayés, Mónica
Heath, Simon
Gut, Marta
Klatt, Peter
Marshall, John
Raine, Keiran
Stebbings, Lucy A.
Futreal, P. Andrew
Stratton, Michael R.
Campbell, Peter J.
Gut, Ivo
López-Guillermo, Armando
Estivill, Xavier
Montserrat, Emili
López-Otín, Carlos
Campo, Elías
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3322590
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3322590
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature10113
