Redox modification of cysteine residues regulates the cytokine activity of high mobility group box-1...
Redox modification of cysteine residues regulates the cytokine activity of high mobility group box-1 (HMGB1)
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Author / Creator
Publisher
England: ScholarOne
Journal title
Language
English
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Publisher
England: ScholarOne
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Scope and Contents
Contents
High mobility group box 1 (HMGB1) is a nuclear protein with extracellular inflammatory cytokine activity. It is released passively during cell injury and necrosis, and secreted actively by immune cells. HMGB1 contains three conserved redox-sensitive cysteine residues: C23 and C45 can form an intramolecular disulfide bond, whereas C106 is unpaired a...
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Full title
Redox modification of cysteine residues regulates the cytokine activity of high mobility group box-1 (HMGB1)
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3324950
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3324950
Other Identifiers
ISSN
1076-1551
E-ISSN
1528-3658
DOI
10.2119/molmed.2011.00389
