Log in to save to my catalogue

Alpharetroviral Self-inactivating Vectors: Long-term Transgene Expression in Murine Hematopoietic Ce...

Alpharetroviral Self-inactivating Vectors: Long-term Transgene Expression in Murine Hematopoietic Ce...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3345992

Alpharetroviral Self-inactivating Vectors: Long-term Transgene Expression in Murine Hematopoietic Cells and Low Genotoxicity

About this item

Full title

Alpharetroviral Self-inactivating Vectors: Long-term Transgene Expression in Murine Hematopoietic Cells and Low Genotoxicity

Publisher

United States: Elsevier Inc

Journal title

Molecular therapy, 2012-05, Vol.20 (5), p.1022-1032

Language

English

Formats

Publication information

Publisher

United States: Elsevier Inc

More information

Scope and Contents

Contents

Comparative integrome analyses have highlighted alpharetroviral vectors with a relatively neutral, and thus favorable, integration spectrum. However, previous studies used alpharetroviral vectors harboring viral coding sequences and intact long-terminal repeats (LTRs). We recently developed self-inactivating (SIN) alpharetroviral vectors with an ad...

Alternative Titles

Full title

Alpharetroviral Self-inactivating Vectors: Long-term Transgene Expression in Murine Hematopoietic Cells and Low Genotoxicity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3345992

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3345992

Other Identifiers

ISSN

1525-0016,1525-0024

E-ISSN

1525-0024

DOI

10.1038/mt.2011.309

How to access this item