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FOXO3a regulates reactive oxygen metabolism by inhibiting mitochondrial gene expression

FOXO3a regulates reactive oxygen metabolism by inhibiting mitochondrial gene expression

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3354049

FOXO3a regulates reactive oxygen metabolism by inhibiting mitochondrial gene expression

About this item

Full title

FOXO3a regulates reactive oxygen metabolism by inhibiting mitochondrial gene expression

Publisher

London: Nature Publishing Group UK

Journal title

Cell death and differentiation, 2012-06, Vol.19 (6), p.968-979

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Forkhead transcription factors of the O class (FOXOs) are important targets of the phosphatidylinositol 3-kinase/Akt pathway, and are key regulators of the cell cycle, apoptosis and response to oxidative stress. FOXOs have been shown to have tumour suppressor function and are important for stem cell maintenance. We have performed a detailed analysi...

Alternative Titles

Full title

FOXO3a regulates reactive oxygen metabolism by inhibiting mitochondrial gene expression

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3354049

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3354049

Other Identifiers

ISSN

1350-9047

E-ISSN

1476-5403

DOI

10.1038/cdd.2011.179

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