Inflammasome-regulated Cytokines Are Critical Mediators of Acute Lung Injury
Inflammasome-regulated Cytokines Are Critical Mediators of Acute Lung Injury
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Full title
Author / Creator
DOLINAY, Tamas , YOUNG SAM KIM , HASPEL, Jeffrey A , LANDAZURY, Roberto , EPPANAPALLY, Sabitha , CHRISTIE, Jason D , MEYER, Nuala J , WARES, Lorraine B , CHRISTIANI, David C , RYTER, Stefan W , BARON, Rebecca M , CHOI, Augustine M. K , HOWRYLAK, Judie , HUNNINGHAKE, Gary M , CHANG HYEOK AN , FREDENBURGH, Laura , MASSARO, Anthony F , ROGERS, Angela , GAZOURIAN, Lee and NAKAHIRA, Kiichi
Publisher
New York, NY: American Thoracic Society
Journal title
Language
English
Formats
Publication information
Publisher
New York, NY: American Thoracic Society
Subjects
More information
Scope and Contents
Contents
Despite advances in clinical management, there are currently no reliable diagnostic and therapeutic targets for acute respiratory distress syndrome (ARDS). The inflammasome/caspase-1 pathway regulates the maturation and secretion of proinflammatory cytokines (e.g., IL-18). IL-18 is associated with injury in animal models of systemic inflammation.
Alternative Titles
Full title
Inflammasome-regulated Cytokines Are Critical Mediators of Acute Lung Injury
Authors, Artists and Contributors
Author / Creator
YOUNG SAM KIM
HASPEL, Jeffrey A
LANDAZURY, Roberto
EPPANAPALLY, Sabitha
CHRISTIE, Jason D
MEYER, Nuala J
WARES, Lorraine B
CHRISTIANI, David C
RYTER, Stefan W
BARON, Rebecca M
CHOI, Augustine M. K
HOWRYLAK, Judie
HUNNINGHAKE, Gary M
CHANG HYEOK AN
FREDENBURGH, Laura
MASSARO, Anthony F
ROGERS, Angela
GAZOURIAN, Lee
NAKAHIRA, Kiichi
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3373064
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3373064
Other Identifiers
ISSN
1073-449X
E-ISSN
1535-4970
DOI
10.1164/rccm.201201-0003OC