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Inflammasome-regulated Cytokines Are Critical Mediators of Acute Lung Injury

Inflammasome-regulated Cytokines Are Critical Mediators of Acute Lung Injury

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3373064

Inflammasome-regulated Cytokines Are Critical Mediators of Acute Lung Injury

About this item

Full title

Inflammasome-regulated Cytokines Are Critical Mediators of Acute Lung Injury

Publisher

New York, NY: American Thoracic Society

Journal title

American journal of respiratory and critical care medicine, 2012-06, Vol.185 (11), p.1225-1234

Language

English

Formats

Publication information

Publisher

New York, NY: American Thoracic Society

More information

Scope and Contents

Contents

Despite advances in clinical management, there are currently no reliable diagnostic and therapeutic targets for acute respiratory distress syndrome (ARDS). The inflammasome/caspase-1 pathway regulates the maturation and secretion of proinflammatory cytokines (e.g., IL-18). IL-18 is associated with injury in animal models of systemic inflammation.

Alternative Titles

Full title

Inflammasome-regulated Cytokines Are Critical Mediators of Acute Lung Injury

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3373064

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3373064

Other Identifiers

ISSN

1073-449X

E-ISSN

1535-4970

DOI

10.1164/rccm.201201-0003OC

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