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Deletion of the epidermal growth factor receptor in renal proximal tubule epithelial cells delays re...

Deletion of the epidermal growth factor receptor in renal proximal tubule epithelial cells delays re...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3376190

Deletion of the epidermal growth factor receptor in renal proximal tubule epithelial cells delays recovery from acute kidney injury

About this item

Full title

Deletion of the epidermal growth factor receptor in renal proximal tubule epithelial cells delays recovery from acute kidney injury

Publisher

Basingstoke: Elsevier Inc

Journal title

Kidney international, 2012-07, Vol.82 (1), p.45-52

Language

English

Formats

Publication information

Publisher

Basingstoke: Elsevier Inc

More information

Scope and Contents

Contents

To determine the role of epidermal growth factor receptor (EGFR) activation in renal functional and structural recovery from acute kidney injury (AKI), we generated mice with a specific EGFR deletion in the renal proximal tubule (EGFRptKO). Ischemia–reperfusion injury markedly activated EGFR in control littermate mice; however, this was inhibited i...

Alternative Titles

Full title

Deletion of the epidermal growth factor receptor in renal proximal tubule epithelial cells delays recovery from acute kidney injury

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3376190

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3376190

Other Identifiers

ISSN

0085-2538,1523-1755

E-ISSN

1523-1755

DOI

10.1038/ki.2012.43

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