Deletion of the epidermal growth factor receptor in renal proximal tubule epithelial cells delays re...
Deletion of the epidermal growth factor receptor in renal proximal tubule epithelial cells delays recovery from acute kidney injury
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Publisher
Basingstoke: Elsevier Inc
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Language
English
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Basingstoke: Elsevier Inc
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Contents
To determine the role of epidermal growth factor receptor (EGFR) activation in renal functional and structural recovery from acute kidney injury (AKI), we generated mice with a specific EGFR deletion in the renal proximal tubule (EGFRptKO). Ischemia–reperfusion injury markedly activated EGFR in control littermate mice; however, this was inhibited i...
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Full title
Deletion of the epidermal growth factor receptor in renal proximal tubule epithelial cells delays recovery from acute kidney injury
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3376190
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3376190
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ISSN
0085-2538,1523-1755
E-ISSN
1523-1755
DOI
10.1038/ki.2012.43