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One Remarkable Molecule: Filaggrin

One Remarkable Molecule: Filaggrin

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3378480

One Remarkable Molecule: Filaggrin

About this item

Full title

One Remarkable Molecule: Filaggrin

Publisher

New York, NY: Elsevier Inc

Journal title

Journal of investigative dermatology, 2012-03, Vol.132 (3), p.751-762

Language

English

Formats

Publication information

Publisher

New York, NY: Elsevier Inc

More information

Scope and Contents

Contents

The discovery, in 2006, that loss-of-function mutations in the filaggrin (FLG) gene are the cause of ichthyosis vulgaris—the most common disorder of keratinization—and also a strong genetic risk factor for atopic eczema, marked a significant breakthrough in the understanding of eczema pathogenesis. Subsequent investigations of the role of FLG-null...

Alternative Titles

Full title

One Remarkable Molecule: Filaggrin

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3378480

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3378480

Other Identifiers

ISSN

0022-202X

E-ISSN

1523-1747

DOI

10.1038/jid.2011.393

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