Molecular mechanism of ATP binding and ion channel activation in P2X receptors
Molecular mechanism of ATP binding and ion channel activation in P2X receptors
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Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
P2X receptors are trimeric ATP-activated ion channels permeable to Na
+
, K
+
and Ca
2+
. The seven P2X receptor subtypes are implicated in physiological processes that include modulation of synaptic transmission, contraction of smooth muscle, secretion of chemical transmitters and regulation of immune responses. Despite the impor...
Alternative Titles
Full title
Molecular mechanism of ATP binding and ion channel activation in P2X receptors
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3391165
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3391165
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature11010
