The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markers
The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markers
About this item
Full title
Author / Creator
Muñoz, Javier , Stange, Daniel E , Schepers, Arnout G , van de Wetering, Marc , Koo, Bon-Kyoung , Itzkovitz, Shalev , Volckmann, Richard , Kung, Kevin S , Koster, Jan , Radulescu, Sorina , Myant, Kevin , Versteeg, Rogier , Sansom, Owen J , van Es, Johan H , Barker, Nick , van Oudenaarden, Alexander , Mohammed, Shabaz , Heck, Albert J R and Clevers, Hans
Publisher
Chichester, UK: John Wiley & Sons, Ltd
Journal title
Language
English
Formats
Publication information
Publisher
Chichester, UK: John Wiley & Sons, Ltd
Subjects
More information
Scope and Contents
Contents
Two types of stem cells are currently defined in small intestinal crypts: cycling crypt base columnar (CBC) cells and quiescent ‘+4’ cells. Here, we combine transcriptomics with proteomics to define a definitive molecular signature for
Lgr5
+
CBC cells. Transcriptional profiling of FACS‐sorted
Lgr5
+
stem cells and their daughters...
Alternative Titles
Full title
The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markers
Authors, Artists and Contributors
Author / Creator
Stange, Daniel E
Schepers, Arnout G
van de Wetering, Marc
Koo, Bon-Kyoung
Itzkovitz, Shalev
Volckmann, Richard
Kung, Kevin S
Koster, Jan
Radulescu, Sorina
Myant, Kevin
Versteeg, Rogier
Sansom, Owen J
van Es, Johan H
Barker, Nick
van Oudenaarden, Alexander
Mohammed, Shabaz
Heck, Albert J R
Clevers, Hans
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3400017
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3400017
Other Identifiers
ISSN
0261-4189
E-ISSN
1460-2075
DOI
10.1038/emboj.2012.166
