Rapid and robust generation of functional oligodendrocyte progenitor cells from epiblast stem cells
Rapid and robust generation of functional oligodendrocyte progenitor cells from epiblast stem cells
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Reported is the robust directed differentiation of mouse epiblast stem cells to oligodendrocyte precursor cells, which then differentiate into myelinating oligodendrocytes
in vitro
and
in vivo
. The system should prove useful for basic research and for drug screens.
Myelin-related disorders such as multiple sclerosis and leukodystrop...
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Full title
Rapid and robust generation of functional oligodendrocyte progenitor cells from epiblast stem cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3400969
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3400969
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ISSN
1548-7091
E-ISSN
1548-7105
DOI
10.1038/nmeth.1712