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Loss of fused in sarcoma (FUS) promotes pathological Tau splicing

Loss of fused in sarcoma (FUS) promotes pathological Tau splicing

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3410390

Loss of fused in sarcoma (FUS) promotes pathological Tau splicing

About this item

Full title

Loss of fused in sarcoma (FUS) promotes pathological Tau splicing

Publisher

Chichester, UK: John Wiley & Sons, Ltd

Journal title

EMBO reports, 2012-08, Vol.13 (8), p.759-764

Language

English

Formats

Publication information

Publisher

Chichester, UK: John Wiley & Sons, Ltd

More information

Scope and Contents

Contents

A subset of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) patients present pathological redistribution and aggregation of the nuclear protein fused in sarcoma (FUS) in the cytoplasm. Although FUS associates with the spliceosomal complex, no endogenous neuronal splicing targets have been identified. Here we identif...

Alternative Titles

Full title

Loss of fused in sarcoma (FUS) promotes pathological Tau splicing

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3410390

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3410390

Other Identifiers

ISSN

1469-221X

E-ISSN

1469-3178

DOI

10.1038/embor.2012.90

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