BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER
BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER
About this item
Full title
Author / Creator
Publisher
Chichester, UK: John Wiley & Sons, Ltd
Journal title
Language
English
Formats
Publication information
Publisher
Chichester, UK: John Wiley & Sons, Ltd
Subjects
More information
Scope and Contents
Contents
In mammalian cells, signal peptide‐dependent protein transport into the endoplasmic reticulum (ER) is mediated by a dynamic protein‐conducting channel, the Sec61 complex. Previous work has characterized the Sec61 channel as a potential ER Ca
2+
leak channel and identified calmodulin as limiting Ca
2+
leakage in a Ca
2+
‐dependent...
Alternative Titles
Full title
BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3411083
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3411083
Other Identifiers
ISSN
0261-4189
E-ISSN
1460-2075
DOI
10.1038/emboj.2012.189
