Harnessing a Physiologic Mechanism for siRNA Delivery With Mimetic Lipoprotein Particles
Harnessing a Physiologic Mechanism for siRNA Delivery With Mimetic Lipoprotein Particles
About this item
Full title
Author / Creator
Nakayama, Tomoko , Butler, James S , Sehgal, Alfica , Severgnini, Mariano , Racie, Tim , Sharman, Jennifer , Ding, Feng , Morskaya, Svetlana Shulga , Brodsky, Joshua , Tchangov, Lubomir , Kosovrasti, Verbena , Meys, Mike , Nechev, Lubomir , Wang, Gang , Peng, Chang Geng , Fang, Yupang , Maier, Martin , Rajeev, Kallanthottathil G , Li, Robert , Hettinger, Julia , Barros, Scott , Clausen, Valerie , Zhang, Xuemei , Wang, Qianfan , Hutabarat, Renta , Dokholyan, Nikolay V , Wolfrum, Christian , Manoharan, Muthiah , Kotelianski, Victor , Stoffel, Markus and Sah, Dinah WY
Publisher
United States: Elsevier Limited
Journal title
Language
English
Formats
Publication information
Publisher
United States: Elsevier Limited
Subjects
More information
Scope and Contents
Contents
Therapeutics based on RNA interference (RNAi) have emerged as a potential new class of drugs for treating human disease by silencing the target messenger RNA (mRNA), thereby reducing levels of the corresponding pathogenic protein. The major challenge for RNAi therapeutics is the development of safe delivery vehicles for small interfering RNAs (siRN...
Alternative Titles
Full title
Harnessing a Physiologic Mechanism for siRNA Delivery With Mimetic Lipoprotein Particles
Authors, Artists and Contributors
Author / Creator
Butler, James S
Sehgal, Alfica
Severgnini, Mariano
Racie, Tim
Sharman, Jennifer
Ding, Feng
Morskaya, Svetlana Shulga
Brodsky, Joshua
Tchangov, Lubomir
Kosovrasti, Verbena
Meys, Mike
Nechev, Lubomir
Wang, Gang
Peng, Chang Geng
Fang, Yupang
Maier, Martin
Rajeev, Kallanthottathil G
Li, Robert
Hettinger, Julia
Barros, Scott
Clausen, Valerie
Zhang, Xuemei
Wang, Qianfan
Hutabarat, Renta
Dokholyan, Nikolay V
Wolfrum, Christian
Manoharan, Muthiah
Kotelianski, Victor
Stoffel, Markus
Sah, Dinah WY
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3412494
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3412494
Other Identifiers
ISSN
1525-0016
E-ISSN
1525-0024
DOI
10.1038/mt.2012.33
