Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations
Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations
About this item
Full title
Author / Creator
Pugh, Trevor J. , Weeraratne, Shyamal Dilhan , Archer, Tenley C. , Pomeranz Krummel, Daniel A. , Auclair, Daniel , Bochicchio, James , Carneiro, Mauricio O. , Carter, Scott L. , Cibulskis, Kristian , Erlich, Rachel L. , Greulich, Heidi , Lawrence, Michael S. , Lennon, Niall J. , McKenna, Aaron , Meldrim, James , Ramos, Alex H. , Ross, Michael G. , Russ, Carsten , Shefler, Erica , Sivachenko, Andrey , Sogoloff, Brian , Stojanov, Petar , Tamayo, Pablo , Mesirov, Jill P. , Amani, Vladimir , Teider, Natalia , Sengupta, Soma , Francois, Jessica Pierre , Northcott, Paul A. , Taylor, Michael D. , Yu, Furong , Crabtree, Gerald R. , Kautzman, Amanda G. , Gabriel, Stacey B. , Getz, Gad , Jäger, Natalie , Jones, David T. W. , Lichter, Peter , Pfister, Stefan M. , Roberts, Thomas M. , Meyerson, Matthew , Pomeroy, Scott L. and Cho, Yoon-Jae
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Medulloblastoma is the most common brain tumour in children; using exome sequencing of tumour samples the authors show that these cancers have low mutation rates and identify 12 significantly mutated genes, among them the gene encoding RNA helicase DDX3X.
The medulloblastoma genome dissected
Medulloblastoma is the most common malignant brain...
Alternative Titles
Full title
Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations
Authors, Artists and Contributors
Author / Creator
Weeraratne, Shyamal Dilhan
Archer, Tenley C.
Pomeranz Krummel, Daniel A.
Auclair, Daniel
Bochicchio, James
Carneiro, Mauricio O.
Carter, Scott L.
Cibulskis, Kristian
Erlich, Rachel L.
Greulich, Heidi
Lawrence, Michael S.
Lennon, Niall J.
McKenna, Aaron
Meldrim, James
Ramos, Alex H.
Ross, Michael G.
Russ, Carsten
Shefler, Erica
Sivachenko, Andrey
Sogoloff, Brian
Stojanov, Petar
Tamayo, Pablo
Mesirov, Jill P.
Amani, Vladimir
Teider, Natalia
Sengupta, Soma
Francois, Jessica Pierre
Northcott, Paul A.
Taylor, Michael D.
Yu, Furong
Crabtree, Gerald R.
Kautzman, Amanda G.
Gabriel, Stacey B.
Getz, Gad
Jäger, Natalie
Jones, David T. W.
Lichter, Peter
Pfister, Stefan M.
Roberts, Thomas M.
Meyerson, Matthew
Pomeroy, Scott L.
Cho, Yoon-Jae
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3413789
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3413789
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature11329
