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SPLUNC1 deficiency enhances airway eosinophilic inflammation in mice

SPLUNC1 deficiency enhances airway eosinophilic inflammation in mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3423460

SPLUNC1 deficiency enhances airway eosinophilic inflammation in mice

About this item

Full title

SPLUNC1 deficiency enhances airway eosinophilic inflammation in mice

Publisher

United States: American Thoracic Society

Journal title

American journal of respiratory cell and molecular biology, 2012-08, Vol.47 (2), p.253-260

Language

English

Formats

Publication information

Publisher

United States: American Thoracic Society

More information

Scope and Contents

Contents

Short palate, lung and nasal epithelium clone 1 (SPLUNC1) is enriched in normal airway lining fluid, but is significantly reduced in airway epithelium exposed to a Th2 cytokine milieu. The role of SPLUNC1 in modulating airway allergic inflammation (e.g., eosinophils) remains unknown. We used SPLUNC1 knockout (KO) and littermate wild-type (C57BL/6 b...

Alternative Titles

Full title

SPLUNC1 deficiency enhances airway eosinophilic inflammation in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3423460

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3423460

Other Identifiers

ISSN

1044-1549

E-ISSN

1535-4989

DOI

10.1165/rcmb.2012-0064OC

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