Inhibition of CXCR2 profoundly suppresses inflammation-driven and spontaneous tumorigenesis
Inhibition of CXCR2 profoundly suppresses inflammation-driven and spontaneous tumorigenesis
About this item
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Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
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Publisher
United States: American Society for Clinical Investigation
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Scope and Contents
Contents
The chemokine receptor CXCR2 is a key mediator of neutrophil migration that also plays a role in tumor development. However, CXCR2 influences tumors through multiple mechanisms and might promote or inhibit tumor development depending on context. Here, we used several mouse models of spontaneous and inflammation-driven neoplasia to define indispensa...
Alternative Titles
Full title
Inhibition of CXCR2 profoundly suppresses inflammation-driven and spontaneous tumorigenesis
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3428079
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3428079
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI61067
