Network Organization of the Huntingtin Proteomic Interactome in Mammalian Brain
Network Organization of the Huntingtin Proteomic Interactome in Mammalian Brain
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Publisher
United States: Elsevier Inc
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Language
English
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Publisher
United States: Elsevier Inc
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Scope and Contents
Contents
We used affinity-purification mass spectrometry to identify 747 candidate proteins that are complexed with Huntingtin (Htt) in distinct brain regions and ages in Huntington's disease (HD) and wild-type mouse brains. To gain a systems-level view of the Htt interactome, we applied Weighted Correlation Network Analysis to the entire proteomic data set...
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Full title
Network Organization of the Huntingtin Proteomic Interactome in Mammalian Brain
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3432264
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3432264
Other Identifiers
ISSN
0896-6273
E-ISSN
1097-4199
DOI
10.1016/j.neuron.2012.05.024
