Structural basis for leucine-rich nuclear export signal recognition by CRM1
Structural basis for leucine-rich nuclear export signal recognition by CRM1
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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CRM1 (also known as XPO1 and exportin 1) mediates nuclear export of hundreds of proteins through the recognition of the leucine-rich nuclear export signal (LR-NES). Here we present the 2.9 Å structure of CRM1 bound to snurportin 1 (SNUPN). Snurportin 1 binds CRM1 in a bipartite manner by means of an amino-terminal LR-NES and its nucleotide-binding...
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Full title
Structural basis for leucine-rich nuclear export signal recognition by CRM1
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3437623
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3437623
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature07975
