Contrasting effects of sunitinib within in vivo models of metastasis
Contrasting effects of sunitinib within in vivo models of metastasis
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Author / Creator
Welti, Jonathan C. , Powles, Thomas , Foo, Shane , Gourlaouen, Morgane , Preece, Natasha , Foster, Julie , Frentzas, Sophia , Bird, Demelza , Sharpe, Kevin , van Weverwijk, Antoinette , Robertson, David , Soffe, Julie , Erler, Janine T. , Pili, Roberto , Springer, Caroline J. , Mather, Stephen J. and Reynolds, Andrew R.
Publisher
Dordrecht: Springer Netherlands
Journal title
Language
English
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Publication information
Publisher
Dordrecht: Springer Netherlands
Subjects
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Scope and Contents
Contents
Sunitinib is a potent and clinically approved tyrosine kinase inhibitor that can suppress tumour growth by inhibiting angiogenesis. However, conflicting data exist regarding the effects of this drug on the growth of metastases in preclinical models. Here we use 4T1 and RENCA tumour cells, which both form lung metastases in Balb/c mice, to re-addres...
Alternative Titles
Full title
Contrasting effects of sunitinib within in vivo models of metastasis
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3496518
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3496518
Other Identifiers
ISSN
0969-6970
E-ISSN
1573-7209
DOI
10.1007/s10456-012-9291-z
