NLRP3 inflammasome activation in macrophage cell lines by prion protein fibrils as the source of IL-...
NLRP3 inflammasome activation in macrophage cell lines by prion protein fibrils as the source of IL-1β and neuronal toxicity
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Publisher
Basel: Springer-Verlag
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Language
English
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Publisher
Basel: Springer-Verlag
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Scope and Contents
Contents
Prion diseases are fatal transmissible neurodegenerative diseases, characterized by aggregation of the pathological form of prion protein, spongiform degeneration, and neuronal loss, and activation of astrocytes and microglia. Microglia can clear prion plaques, but on the other hand cause neuronal death via release of neurotoxic species. Elevated e...
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Full title
NLRP3 inflammasome activation in macrophage cell lines by prion protein fibrils as the source of IL-1β and neuronal toxicity
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3508391
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3508391
Other Identifiers
ISSN
1420-682X
E-ISSN
1420-9071
DOI
10.1007/s00018-012-1140-0
