Identification of fifteen new psoriasis susceptibility loci highlights the role of innate immunity
Identification of fifteen new psoriasis susceptibility loci highlights the role of innate immunity
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Author / Creator
Tsoi, Lam C , Spain, Sarah L , Knight, Jo , Ellinghaus, Eva , Stuart, Philip E , Capon, Francesca , Ding, Jun , Li, Yanming , Tejasvi, Trilokraj , Gudjonsson, Johann E. , Kang, Hyun M , Allen, Michael H , McManus, Ross , Novelli, Giuseppe , Samuelsson, Lena , Schalkwijk, Joost , Ståhle, Mona , Burden, A. David , Smith, Catherine H , Cork, Michael J , Estivill, Xavier , Bowcock, Anne M , Krueger, Gerald G. , Weger, Wolfgang , Worthington, Jane , Tazi-Ahnini, Rachid , Nestle, Frank O , Hayday, Adrian , Hoffmann, Per , Winkelmann, Juliane , Wijmenga, Cisca , Langford, Cordelia , Edkins, Sarah , Andrews, Robert , Blackburn, Hannah , Strange, Amy , Band, Gavin , Pearson, Richard D , Vukcevic, Damjan , Spencer, Chris CA , Deloukas, Panos , Mrowietz, Ulrich , Schreiber, Stefan , Weidinger, Stephan , Koks, Sulev , Kingo, Külli , Esko, Tonu , Metspalu, Andres , Lim, Henry W , Voorhees, John J , Weichenthal, Michael , Wichmann, H. Erich , Chandran, Vinod , Rosen, Cheryl F , Rahman, Proton , Gladman, Dafna D , Griffiths, Christopher EM , Reis, Andre , Kere, Juha , Nair, Rajan P , Franke, Andre , Barker, Jonathan NWN , Abecasis, Goncalo R , Elder, James T and Trembath, Richard C
Journal title
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English
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Contents
To gain further insight into the genetic architecture of psoriasis, we conducted a meta-analysis of three genome-wide association studies (GWAS) and two independent datasets genotyped on the Immunochip, involving 10,588 cases and 22,806 controls in total. We identified 15 new disease susceptibility regions, increasing the number of psoriasis-associ...
Alternative Titles
Full title
Identification of fifteen new psoriasis susceptibility loci highlights the role of innate immunity
Authors, Artists and Contributors
Author / Creator
Spain, Sarah L
Knight, Jo
Ellinghaus, Eva
Stuart, Philip E
Capon, Francesca
Ding, Jun
Li, Yanming
Tejasvi, Trilokraj
Gudjonsson, Johann E.
Kang, Hyun M
Allen, Michael H
McManus, Ross
Novelli, Giuseppe
Samuelsson, Lena
Schalkwijk, Joost
Ståhle, Mona
Burden, A. David
Smith, Catherine H
Cork, Michael J
Estivill, Xavier
Bowcock, Anne M
Krueger, Gerald G.
Weger, Wolfgang
Worthington, Jane
Tazi-Ahnini, Rachid
Nestle, Frank O
Hayday, Adrian
Hoffmann, Per
Winkelmann, Juliane
Wijmenga, Cisca
Langford, Cordelia
Edkins, Sarah
Andrews, Robert
Blackburn, Hannah
Strange, Amy
Band, Gavin
Pearson, Richard D
Vukcevic, Damjan
Spencer, Chris CA
Deloukas, Panos
Mrowietz, Ulrich
Schreiber, Stefan
Weidinger, Stephan
Koks, Sulev
Kingo, Külli
Esko, Tonu
Metspalu, Andres
Lim, Henry W
Voorhees, John J
Weichenthal, Michael
Wichmann, H. Erich
Chandran, Vinod
Rosen, Cheryl F
Rahman, Proton
Gladman, Dafna D
Griffiths, Christopher EM
Reis, Andre
Kere, Juha
Nair, Rajan P
Franke, Andre
Barker, Jonathan NWN
Abecasis, Goncalo R
Elder, James T
Trembath, Richard C
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3510312
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3510312
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.2467
