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Environmental toxins trigger PD-like progression via increased alpha-synuclein release from enteric...

Environmental toxins trigger PD-like progression via increased alpha-synuclein release from enteric...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3510466

Environmental toxins trigger PD-like progression via increased alpha-synuclein release from enteric neurons in mice

About this item

Full title

Environmental toxins trigger PD-like progression via increased alpha-synuclein release from enteric neurons in mice

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2012-11, Vol.2 (1), p.898

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Pathological studies on Parkinson's disease (PD) patients suggest that PD pathology progresses from the enteric nervous system (ENS) and the olfactory bulb into the central nervous system. We have previously shown that environmental toxins acting locally on the ENS mimic this PD-like pathology progression pattern in mice. Here, we show for the firs...

Alternative Titles

Full title

Environmental toxins trigger PD-like progression via increased alpha-synuclein release from enteric neurons in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3510466

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3510466

Other Identifiers

E-ISSN

2045-2322

DOI

10.1038/srep00898

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