An ex Vivo Model for Imprinting: Mutually Exclusive Binding of Cdx2 and Oct4 as a Switch for Imprint...
An ex Vivo Model for Imprinting: Mutually Exclusive Binding of Cdx2 and Oct4 as a Switch for Imprinted and Random X-Inactivation
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United States: Genetics Society of America
Journal title
Language
English
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United States: Genetics Society of America
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Contents
In the early mammalian embryo, X chromosome inactivation (XCI) achieves dosage parity between males and females for X-linked genes. During mouse development, imprinted paternal XCI is observed first and switches to random XCI in the epiblast but not placental lineages. The mechanism by which this epigenetic switch occurs is currently unknown. Here,...
Alternative Titles
Full title
An ex Vivo Model for Imprinting: Mutually Exclusive Binding of Cdx2 and Oct4 as a Switch for Imprinted and Random X-Inactivation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3522163
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3522163
Other Identifiers
ISSN
1943-2631,0016-6731
E-ISSN
1943-2631
DOI
10.1534/genetics.112.144121
