Impaired thermogenesis and adipose tissue development in mice with fat-specific disruption of insuli...
Impaired thermogenesis and adipose tissue development in mice with fat-specific disruption of insulin and IGF-1 signalling
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Insulin and insulin-like growth factor 1 (IGF-1) have important roles in adipocyte differentiation, glucose tolerance and insulin sensitivity. Here to assess how these pathways can compensate for each other, we created mice with a double tissue-specific knockout of insulin and IGF-1 receptors to eliminate all insulin/IGF-1 signalling in fat. These...
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Full title
Impaired thermogenesis and adipose tissue development in mice with fat-specific disruption of insulin and IGF-1 signalling
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3529640
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3529640
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms1905
